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MLH1 Monoclonal Antibody

No Catalog : BZ-085401-AM

Reactivity : Human,Monkey

Source : Mouse

Type : Monoclonal

Application : IHC-p WB ELISA IF

MutL homolog 1(MLH1) Homo sapiens This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.

MLH1; COCA2; DNA mismatch repair protein Mlh1; MutL protein homolog 1.
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