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IL-1 Beta Monoclonal Antibody

No Catalog : BZ-088670-AM

Reactivity : Human

Source : Mouse

Type : Monoclonal

Application : IHC-p WB ELISA IF

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction ofcyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.

IL1B; IL1F2; Interleukin-1 beta; IL-1 beta; Catabolin.
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