SLC2A4 is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes Solute carrier family 2 facilitated glucose transporter member 4 that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, solute carrier family 2 facilitated glucose transporter member 4 is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, solute carrier family 2 facilitated glucose transporter member 4 moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM).

SLC2A4; GLUT4; Solute carrier family 2; facilitated glucose transporter member 4; Glucose transporter type 4, insulin-responsive; GLUT-4