The protein encoded by SOD1 (superoxide dismutase 1, soluble) binds copper and zinc ions and isone of two isozymes responsible for destroying free superoxide radicals in the body. The encodedisozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring butharmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is amitochondrial protein. Mutations in SOD1 have been implicated as causes of familial amyotrophiclateral sclerosis. Rare transcript variants have been reported for SOD1.

SOD1; Superoxide dismutase [Cu-Zn]; Superoxide dismutase 1;hSod1